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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPC1
All Species:
15.76
Human Site:
S274
Identified Species:
43.33
UniProt:
Q03188
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03188
NP_001803
943
106926
S274
L
E
T
V
K
R
K
S
E
S
S
P
I
V
R
Chimpanzee
Pan troglodytes
XP_001164757
943
106900
S274
L
E
T
V
K
R
K
S
E
S
S
P
I
V
R
Rhesus Macaque
Macaca mulatta
XP_001099283
1042
117300
S371
L
E
T
V
K
R
K
S
K
S
S
P
V
V
R
Dog
Lupus familis
XP_532388
940
106041
S268
L
E
T
V
K
R
K
S
E
S
S
P
V
V
R
Cat
Felis silvestris
Mouse
Mus musculus
P49452
906
102207
P259
T
A
A
V
P
F
S
P
P
P
P
S
D
M
K
Rat
Rattus norvegicus
NP_001004098
916
103315
S264
V
N
R
K
S
K
C
S
S
V
V
R
H
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990382
872
97219
N225
W
F
S
I
P
R
K
N
R
K
S
Q
K
D
G
Frog
Xenopus laevis
NP_001159485
1400
156033
T549
S
M
F
L
Q
A
A
T
Q
G
H
A
T
R
Y
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001187228
1303
143749
K411
R
K
S
T
R
Q
S
K
V
N
D
A
V
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
81.7
67.8
N.A.
51.4
54.1
N.A.
N.A.
25.4
22.2
N.A.
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
100
99.4
85.4
79
N.A.
65
68.7
N.A.
N.A.
44.8
37.5
N.A.
N.A.
N.A.
N.A.
N.A.
38.3
P-Site Identity:
100
100
86.6
93.3
N.A.
6.6
6.6
N.A.
N.A.
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
20
20
N.A.
N.A.
40
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
0
0
12
12
0
0
0
0
23
0
0
12
% A
% Cys:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
12
0
12
23
12
% D
% Glu:
0
45
0
0
0
0
0
0
34
0
0
0
0
0
0
% E
% Phe:
0
12
12
0
0
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
12
0
0
% H
% Ile:
0
0
0
12
0
0
0
0
0
0
0
0
23
0
0
% I
% Lys:
0
12
0
12
45
12
56
12
12
12
0
0
12
0
12
% K
% Leu:
45
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
12
0
0
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
12
0
0
0
0
0
12
0
12
0
0
0
0
0
% N
% Pro:
0
0
0
0
23
0
0
12
12
12
12
45
0
0
0
% P
% Gln:
0
0
0
0
12
12
0
0
12
0
0
12
0
0
0
% Q
% Arg:
12
0
12
0
12
56
0
0
12
0
0
12
0
12
45
% R
% Ser:
12
0
23
0
12
0
23
56
12
45
56
12
0
0
0
% S
% Thr:
12
0
45
12
0
0
0
12
0
0
0
0
12
12
0
% T
% Val:
12
0
0
56
0
0
0
0
12
12
12
0
34
45
0
% V
% Trp:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _